Cross-linked esters of hyaluronic acid

Patent 4957744 Issued on September 18, 1990. Estimated Expiration Date:

October 13, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

Multilayer membrane useful as synthetic skin
Patent #: 4060081
Issued on: 11/29/1977
Inventor: Yannas , et al.

Ultrapure hyaluronic acid and the use thereof
Patent #: 4141973
Issued on: 02/27/1979
Inventor: Balazs

Crosslinked collagen-mucopolysaccharide composite materials
Patent #: 4280954
Issued on: 07/28/1981
Inventor: Yannas , et al.

Methylolated mono- and oligosaccharides
Patent #: 4322523
Issued on: 03/30/1982
Inventor: Wagner

Ophthalmological procedures
Patent #: 4328803
Issued on: 05/11/1982
Inventor: Pape

Heparin esters and processes for their preparation
Patent #: 4440926
Issued on: 04/03/1984
Inventor: Mardiguian

Polymeric articles modified with hyaluronate
Patent #: 4487865
Issued on: 12/11/1984
Inventor: Balazs , et al.

Hyaluronate modified polymeric articles
Patent #: 4500676
Issued on: 02/19/1985
Inventor: Balazs , et al.

Cross-linked gels of hyaluronic acid and products containing such gels
Patent #: 4582865
Issued on: 04/15/1986
Inventor: Balazs , et al.

Cross-linked gels of hyaluronic acid and products containing such gels
Patent #: 4605691
Issued on: 08/12/1986
Inventor: Balazs , et al.

More ...

Inventors

Assignee

Fidia S.p.A.

Application

No. 106658 filed on 10/13/1987

US Classes:

424/401, Cosmetic, antiperspirant, dentifrice424/423, Surgical implant or material424/443, Web, sheet or filament bases; compositions of bandages; or dressings with incorporated medicaments424/451, Capsules (e.g., of gelatin, of chocolate, etc.)424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)512/5, Animal or plant extract active ingredient514/54, Polysaccharide514/844, COSMETIC, FACIAL514/880, HAIR TREATMENT (THERAPEUTIC-SCALP)536/55.1Polysaccharides

Examiners

Primary: Rollins, John W.
Assistant: Peselev, Elli

Attorney, Agent or Firm

Birch, Stewart, Kolasch & Birch

Foreign Patent References

0044228 EP. 01/13/1982
0161887 EP. 11/13/1985
0193510 EP. 09/13/1986
0216453 EP. 04/13/1987
0224987 EP. 06/13/1987
0280807 EP. 09/13/1988
0291177 EP. 11/13/1988
3434082 DE. 09/13/1984
2478468 FR. 09/13/1981
WO86/00079 WO. 01/13/1986
WO87/07898 WO. 12/13/1987
2151244 GB. 07/13/1985
2160097 GB. 12/13/1985
2185397 GB. 07/13/1987

International Classes

A61K 031/70
C07G 003/00
C07H 001/00

Foreign Application Priority Data

1986-10-13 IT

Abstract

Cross-linked esters of hyaluronic acid are provided which result from the esterification of polyhydric alcohols with two or more carboxy groups of the hyaluronic acid polysaccharide. These cross-linked esters are useful in the field of biodegradable plastics for sanitary and surgical articles and in the pharmaceutical and cosmetic fields for the preparation of useful compositions and articles.