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US Patent 4957730 - Antimycotic nail varnish

US Patent Issued on September 18, 1990
Estimated Patent Expiration Date: Icon_subject September 18, 2007Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

A nail varnish comprising a water-insoluble film-forming substance and an antimycotic compound which is a 1-hydroxy-2-pyridone I of the general formula ##STR1## in which R1 is a hydrocarbon group which contains from 6 to 9 carbon atoms, but is free from olefinic and acetylenic bonds, one of the groups R2 and R4 is hydrogen and the other is hydrogen, methyl or ethyl and R3 is alkyl having up to two carbon atoms, said antimycotic ingredient being present in free form or in the form of a salt.

Other References

  • Dittmar et al., C.A., 92:47183b, Feb. 1980, No. 6
  • Lohaus et al., Arzneimittel Forschung (Drug Research) 31, (II) 1981, pp. 1311-1316
  • Fungiplex Nail Varnish, Prospectus of Hermal-Chemie Kurt Herrmann, Hamburg, Fed. Rep. of Germany
  • O. Male, Therapie der Pilzkrankheiten, WMW Sonderheft 1/1983, pp. 27-34
  • Aldrich, p. 860 (1988)
  • Kellner et al, Chem. Abstracts, 95, 225547v, (1981

Inventors

Application

No. 942699 filed on 12/17/1986

US Classes:

424/61, MANICURE OR PEDICURE COMPOSITIONS514/345, Chalcogen bonded directly to ring carbon of the six-membered hetero ring546/290Chalcogen bonded directly to ring carbon of the six-membered hetero ring

Field of Search

424/61, MANICURE OR PEDICURE COMPOSITIONS546/290, Chalcogen bonded directly to ring carbon of the six-membered hetero ring514/345Chalcogen bonded directly to ring carbon of the six-membered hetero ring

Examiners

Primary: Rollins, John W.
Assistant: Catchpole, W.

Attorney, Agent or Firm

US Patent References

2752356, 3269904, 3883545, 3968118, Process for the manufacture of 1-hydroxy-2-pyridones
Issued on: 07/06/1976
Inventor: Lohaus ,   et al.
4185106, Pyridones as antidandruff agents
Issued on: 01/22/1980
Inventor: Dittmar ,   et al.
4250164Method of treating psoriasis of the nails and composition
Issued on: 02/10/1981
Inventor: Bernstein

Foreign Patent References

  • 1175355 CA. 10/16/1984
  • 0055397 EP. 08/16/1984
  • 0140325 EP. 05/16/1985
  • 1795831 DE. 05/16/1976
  • 3140054 DE. 05/16/1983
  • 87/02580 WO. 05/16/1987

International Class

A61K 007/043

Foreign Application Priority Data

1985-12-19 DE

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