Penetrating topical pharmaceutical compositions
Patent 4954487 Issued on September 4, 1990. Estimated Expiration Date: 
February 15, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 15, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 2990331 3535422 3592930 3888995 3924004 Potentiated medicaments Steroid ointment Process for the treatment of acarid skin infections in animals Topical composition containing acetyl salicylic acid Anti-acne composition InventorsAssigneeApplicationNo. 312354 filed on 02/15/1989US Classes:514/159, Ortho-hydroxybenzoic acid (i.e., salicyclic acid) or derivative DOAI514/420, Indomethacine per se or ester thereof514/569, Polycyclo ring system514/570, Carboxy or salt thereof only attached indirectly to the benzene ring514/947Topical applicationExaminersPrimary: Schenkman, LeonardAttorney, Agent or FirmForeign Patent References
International ClassA61K 031/60AbstractA large group of lipophilic, pharmacologically active compounds can be effectively delivered across intact skin by applying them topically in a binary, penetration-enhancing vehicle containing (1) a C3 -C4 diol, diol ester, or diol ether and (2) a cell envelope-disordering compound. This vehicle provides surprising enhancement of skin penetration for the pharmacological active, compared to either component alone.Other References
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