U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Irradiation of blood products

Patent 4952812 Issued on August 28, 1990. Estimated Expiration Date: Icon_subject May 2, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

2001555

Method and apparatus for treating flowable material
Patent #: 4048504
Issued on: 09/13/1977
Inventor: Bosshard

Method for externally treating the blood
Patent #: 4398906
Issued on: 08/16/1983
Inventor: Edelson

Apparatus for irradiating tubing connections
Patent #: 4433244
Issued on: 02/21/1984
Inventor: Hogan

Sterilization method
Patent #: 4448750
Issued on: 05/15/1984
Inventor: Fuesting

UV Stabilizer system and UV stabilized polyolefins
Patent #: 4487870
Issued on: 12/11/1984
Inventor: Bartz

Undenatured virus-free biologically active protein derivatives
Patent #: 4540573
Issued on: 09/10/1985
Inventor: Neurath ,   et al.

Storm window film
Patent #: 4590124
Issued on: 05/20/1986
Inventor: Schoenberg

Biocompatible method for in situ production of functional platelets and product produced thereby lacking immunogenicity
Patent #: 4608255
Issued on: 08/26/1986
Inventor: Kahn ,   et al.

Method and system for externally treating the blood
Patent #: 4612007
Issued on: 09/16/1986
Inventor: Edelson

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Inventors

Assignee

Application

No. 346202 filed on 05/02/1989

US Classes:

250/455.11, Source and object encasement (e.g., sterilizers)250/492.1, IRRADIATION OF OBJECTS OR MATERIAL422/24Ultraviolet

Examiners

Primary: Howell, Daniel W.
Assistant: Nguyen, Hiep T.

Attorney, Agent or Firm

International Class

A61N 005/06

Abstract

A thin film or layer of white blood cells, such as the contaminating white cells in a platelet concentrate, is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 20 milliwatts per square cm. to provide a total energy exposure of typically 800 to 20,000 millijoules per square cm. of ultraviolet radiation. The white blood cells so produced substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation. Novel irradiating devices are also disclosed.

Other References

  • Bredberg et al.--Chemical Abstracts, vol. 101 (1984) p. 146941h
  • Lagner et al.--Chemical Abstracts, vol. 88 (1978) p. 31915y
  • Lynch et al.--Chemical Abstracts, vol. 99 (1983) p. 172086t
  • Krylenkov et al.--Chemical Abstracts, vol. 101 (1984) p. 206812
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