Patent References 2001555 Method and apparatus for treating flowable material Method for externally treating the blood Apparatus for irradiating tubing connections Sterilization method UV Stabilizer system and UV stabilized polyolefins Undenatured virus-free biologically active protein derivatives Storm window film Biocompatible method for in situ production of functional platelets and product produced thereby lacking immunogenicity Method and system for externally treating the blood InventorsAssigneeApplicationNo. 346202 filed on 05/02/1989US Classes:250/455.11, Source and object encasement (e.g., sterilizers)250/492.1, IRRADIATION OF OBJECTS OR MATERIAL422/24UltravioletExaminersPrimary: Howell, Daniel W.Assistant: Nguyen, Hiep T. Attorney, Agent or FirmInternational ClassA61N 005/06AbstractA thin film or layer of white blood cells, such as the contaminating white cells in a platelet concentrate, is irradiated with ultraviolet radiation predominately of a wavelength of 280 to 320 nanometers, and preferably at an intensity of 4 to 20 milliwatts per square cm. to provide a total energy exposure of typically 800 to 20,000 millijoules per square cm. of ultraviolet radiation. The white blood cells so produced substantially lose their capability to set off an immune reaction in an alloimmunized patient. The white blood cells may preferably be placed into such film in a flat, flexible bag made of poly(ethylene-vinyl acetate) plastic, with the flat, flexible bag being stretched in a direction normal to the path of ultraviolet radiation. Novel irradiating devices are also disclosed.Other References
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