U.S. patents available from 1976 to present.
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Glyphosate-resistant plants

Patent 4940835 Issued on July 10, 1990. Estimated Expiration Date: Icon_subject July 10, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase, production and use
Patent #: 4535060
Issued on: 08/13/1985
Inventor: Comai

Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthase, production and use Patent #: 4769061
Issued on: 09/06/1988
Inventor: Comai

Inventors

Application

No. 879814 filed on 07/07/1986

US Classes:

800/288, Nonplant protein is expressed from the polynucleotide435/320.1, VECTOR, PER SE (E.G., PLASMID, HYBRID PLASMID, COSMID, VIRAL VECTOR, BACTERIOPHAGE VECTOR, ETC.) BACTERIOPHAGE VECTOR, ETC.)435/411, Tomato cell or cell line, per se435/414, Tobacco cell or cell line, per se435/415, Soybean cell or cell line, per se435/416, Sunflower cell or cell line, per se435/418, Plant cell or cell line, per se, is pest or herbicide resistant or pest lethal536/23.6, Encodes a plant polypeptide536/24.1, Non-coding sequences which control transcription or translation processes (e.g., promoters, operators, enhancers, ribosome binding sites, etc.)800/294, Via Agrobacterium800/300, Herbicide resistant plant which is transgenic or mutant800/300.1The plant is maize

Examiners

Primary: Warren, Charles F.
Assistant: Fox, David T.

Attorney, Agent or Firm

Foreign Patent References

  • 0115673 EP 08/13/1984

International Classes

A01H 001/04
C12N 015/00
C12N 005/00
C07H 015/12

Abstract

This invention involves a cloning or expression vector comprising a gene which encodes 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) polypeptide which, when expressed in a plant cell contains a chloroplast transit peptide which allows the polypeptide, or an enzymatically active portion thereof, to be transported from the cytoplasm of the plant cell into a chloroplast in the plant cell, and confers a substantial degree of glyphosate resistance upon the plant cell and plants regenerated therefrom.The EPSPS coding sequence may be ligated to a strong promoter, such as the 35S promoter from cauliflower mosaic virus, to create a chimeric gene. Such genes can be inserted into plant transformation vectors, and subsequently introduced into plant cells. Plant cells transformed using such genes and plants regenerated therefrom have been shown to exhibit a substantial degree of glyphosate resistance.

Other References

  • Smart et al., J. of Biol. Chem (1985) 260, 30, pp. 16338-16346
  • Lee, T. T., J. Plant Growth Regul (1982) 1:37-48
  • Jensen, R. A., Physiol. Plant (1985) 66:164-168
  • Rubin et al., Plant Physiol. (1982) 70, 833-839
  • Mousdale et al., Planta (1985) 163:241-249
  • 'dAmato, T. A., et al., Planta (1984) 162:104-108
  • Rothe, G. M., et al. Planta (1983) 157:358-366
  • Singh et al., Arch. of Biochem & Bioph. (1985) 243:2 pp. 374-384
  • Saijo et al., Agric. Biol. Chem (1979) 43 (7) pp. 1427-1432
  • Schmidt et al., P.N.A.S. (1983) 80, 2632-2636
  • Stalker et al., J. Biol. Chem (1985) 260:8 pp. 4724-4728
  • Science (1986) 231: 1360-1361
  • Biotechnology (1984) Nov., pp. 944
  • Cole et al., Weed Research (1983) 23, 173-183
  • Rubin et al. Plant Physiol. (1984)75, pp. 839-945
  • Guilley et al. (1982) "Transcription of CAMV DNA. . ." Cell 30: 763-73
  • Mazur et al. (1985) "Cloning Herbicide. . . " World Biotech Rep 2: 97-108
  • Goodman et al. (1987) "Gene Transfer in Crop. . ." Science 236: 48-54
  • Amrheim et al. (1983) "Biochemical Basis For. . ." FEBS Letters 157: 191-6
  • Najziger et al. (1984) "Selection & Characterization. . ." Plant Physiol 76: 571-4
  • Vanden Broeck et al. (1985) "Targeting of. . ." Nature 313: 358-63
  • Koziel et al. (1984) "A Cauliflower Mosiac Virus. . ." J. Mol. Appl. Genet 2: 549-62
  • Rogers et al (1983) Appl. Environ Microbiol 46 : 37-43
  • Comai et al. (1983) Science 221: 370-
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