U.S. patents available from 1976 to present.
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Use of N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine

Patent 4939175 Issued on July 3, 1990. Estimated Expiration Date: Icon_subject March 29, 2009. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Arylcyclobutylalkylamines and anti-depression composition and methods using same
Patent #: 4443449
Issued on: 04/17/1984
Inventor: Jeffery ,   et al.

Therapeutic agents
Patent #: 4522828
Issued on: 06/11/1985
Inventor: Jeffery ,   et al.

Therapeutic agents
Patent #: 4746680
Issued on: 05/24/1988
Inventor: Jeffery ,   et al.

Therapeutic agents
Patent #: 4767790
Issued on: 08/30/1988
Inventor: Jeffery ,   et al.

Therapeutic agents
Patent #: 4806570
Issued on: 02/21/1989
Inventor: Jeffery ,   et al.

Therapeutic agents
Patent #: 4814352
Issued on: 03/21/1989
Inventor: Jeffery ,   et al.

Method of treatment
Patent #: 4816488
Issued on: 03/28/1989
Inventor: Rees

Medical treatment Patent #: 4871774
Issued on: 10/03/1989
Inventor: Rees

Inventors

Assignee

Application

No. 330012 filed on 03/29/1989

US Classes:

514/646Benzene ring containing

Examiners

Primary: Friedman, Stanley J.

Attorney, Agent or Firm

Foreign Patent References

  • 2098602A GB. 11/13/1982
  • 2184122A GB. 06/13/1987

International Class

A61K 031/135

Foreign Application Priority Data

1988-03-31 JP

Abstract

Use of N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutylamine or a pharmacologically acceptable acid addition salt thereof for manufacture of a cerebral function improver for the treatment of cerebral function disorders, which is useful as an improver for cerebral function disorders such as amnestic syndrome, senile dementia and Parkinson's disease, since it can intensively activate the central nervous system, especially dopamine neuron, and also increase the spontaneous movement in human or animal.

Other References

  • Chem. Abst. 109 (1988)-204745a
  • Buckett et al., "Prog. Nuero-Psychopharmacol. & Biol. Psychiat", The Pharmacology of Sibutramine Hydrochloride, 1988, vol. 12, pp. 575-584
  • Luscombe, et al., "British Journal of Pharmaceology", vol. 92, Dec. 1987, Sep. 9-11, 1987
  • Buckett, et al., "British Journal of Pharmaceology", vol. 90, Mar. 1987, Dec. 17-19, 198
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