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US Patent 4939147 - Substituted 3,4-dihydroxy phenylethylamino compounds

US Patent Issued on July 3, 1990
Estimated Patent Expiration Date: Icon_subject August 2, 2009Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

Compounds of the formula, ##STR1## in which one of R30 and R40 represents a substituted phenylalkyl group and the other of R30 and R40 represents hydrogen or halogen, and R50 and R60 each independently represent hydrogen or alkyl.The compounds of the invention are useful for the treatment or prophylaxis of renal failure or cardiovascular disease.

Inventors

Assignee

Application

No. 388383 filed on 08/02/1989

US Classes:

514/603, Nitrogen in Q514/616, Plural carboxamide groups or plural C=O groups bonded directly to the same nitrogen514/649, Amino nitrogen attached to aryl ring or aryl ring system by an acyclic carbon or acyclic chain564/82, Plural sulfonamide groups containing or containing plural sulfonyls bonded directly to the same nitrogen564/85, Sulfur in substituent Q564/86, Nitrogen in substituent Q564/87, Nitro or nitroso in substituent Q564/89, Hydroxy, bonded directly to carbon, or ether in substituent Q (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)564/152, Plural carboxamide groups containing or containing plural carbonyls bonded directly to the same nitrogen564/153, Three or more carboxamide groups564/154, Sulfur containing564/155, Benzene ring containing564/157, Amino nitrogen, not bonded directly to carbonyl, containing564/158, Hydroxy, bonded directly to carbon, or ether containing (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)564/162, Sulfur in substituent Q564/165, Hydroxy, bonded directly to carbon, or ether in substituent Q (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)564/166, Nitro in substituent Q564/280, Phenol or thiophenol addition salts564/305, Benzene ring containing564/336Amino nitrogen attached to aryl ring or ring system by an acyclic carbon or chain

Field of Search

564/305, Benzene ring containing564/280, Phenol or thiophenol addition salts564/165, Hydroxy, bonded directly to carbon, or ether in substituent Q (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)564/82, Plural sulfonamide groups containing or containing plural sulfonyls bonded directly to the same nitrogen564/89, Hydroxy, bonded directly to carbon, or ether in substituent Q (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)564/85, Sulfur in substituent Q564/86, Nitrogen in substituent Q564/87, Nitro or nitroso in substituent Q564/152, Plural carboxamide groups containing or containing plural carbonyls bonded directly to the same nitrogen564/153, Three or more carboxamide groups564/154, Sulfur containing564/155, Benzene ring containing564/157, Amino nitrogen, not bonded directly to carbonyl, containing564/158, Hydroxy, bonded directly to carbon, or ether containing (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)564/162, Sulfur in substituent Q564/166, Nitro in substituent Q514/603, Nitrogen in Q514/616, Plural carboxamide groups or plural C=O groups bonded directly to the same nitrogen514/644Amine oxides

Examiners

Primary: Raymond, Richard L.
Assistant: Covington, Raymond

Attorney, Agent or Firm

US Patent References

3408396

Foreign Patent References

  • 1191846 CA 08/16/1985
  • 0142283 EP. 05/16/1985
  • 0188361 EP. 07/16/1986
  • 3428526 DE 02/16/1986

International Classes

A01N 037/30
C07C 087/28

Foreign Application Priority Data

1987-05-19 GB

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