Mechanically scanned line-focus ultrasound hyperthermia system

Patent 4938216 Issued on July 3, 1990. Estimated Expiration Date:

June 21, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

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Inventor

Lele, Padmakar P.

Application

No. 209519 filed on 06/21/1988

US Classes:

601/3, Hyperthermia73/642Having wave shaping means

Examiners

Primary: Cohen, Lee S.

Attorney, Agent or Firm

Engellenner; Thomas J., Jacobs; David A.

Foreign Patent References

0214782 EP 03/13/1987

International Class

A61N 005/00

Abstract

A therapeutic hyperthermia system generates a line-focus beam of ultrasound which can be mechanically scanned across a treatment volume of tissue. The ultilization of a line-focus advantageously reduces the peak intensity of the ultrasonic beam. The system includes methods of scanning the line-focus beam to provide optimal treatment protocols for deep tumors and other pathological conditions while minimizing damage in overlying body tissues. The utilization of mechanical scanning reduces the number of transducers, amplifiers and associated electronics required.

Other References

Lele, P. P., 1975, "Hyperthermia by Ultrasound", Proceedings of the International Symposium on Cancer Therapy by Hyperthermia and Radiation, American College of Radiology, Washington, D.C., pp. 168-178
Lele, P. P., 1981, "An Annular-Focus Ultrasonic Lens for Production of Uniform Hyperthermia in Cancer Therapy", Ultrasound in Medicine and Biology, pp. 191-193
Lele, P. P., 1983, "Physical Aspects and Clinical Studies with Ultrasonic Hyperthermia", Hyperthermia in Cancer Therapy, G. K. Hall and Co., pp. 333-367
Sleefe, G. E. and Lele, P. P., 1985, "Phased Arrays for the Induction of Local Hyperthermia", Proceedings of the IEEE 1985 Ultrasonics Symposium
Lele, P. P., 1986, "Rationale, Technique and Clinical Results with Scanned, Focused Ultrasound (SIMFU) System", IEEE Eighth Annual Conference of the Engineering in Medicine and Biology Society
Lele, P. P., 1987, "Ultrasound: Synergistic Effects and Application in Cancer Therapy by Hyperthermia", Ultrasound, Plenum Publishing Corporation, pp. 307-332
Lele, P. P., 1987, "Effects of Ultrasound on `Solid` Mamalian Tissues and Tumors in Vivo", "Ultrasound", Plenum Publishing Corporation, pp. 275-306
Lele, P. P. and J. Goddard, 1987, "Optimizing Insonation Parameters in Therapy Planning for Deep Heating by SIMFU", IEEE Ninth Annual Conference of the Engineering in Medicine and Biology Society
Lele, P. P., Goddard, J. Blanter, M., 1987, "Clinical Results with Scanned, Intensity-Modulated, Focused Ultrasound (SIMFU) System", Proceedings of 73rd Annual Meeting, Radiological Society of North America, pp. 157-17