ApplicationNo. 896418 filed on 08/13/1986
US Classes:435/14, Involving glucose or galactose422/56, Having reagent in absorbent or bibulous substrate422/57, Having coated reagent422/58, In holder or container having special form422/61, Test package or kit422/68.1, Means for analyzing liquid or solid sample435/4, MEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP435/25, Involving oxidoreductase435/28, Involving peroxidase435/805, TEST PAPERS435/808, OPTICAL SENSING APPARATUS435/810, PACKAGED DEVICE OR KIT436/24, Wine or alcoholic beverages436/46, With sample on test slide436/63, BIOLOGICAL CELLULAR MATERIAL TESTED436/95, Glucose436/166, Including reagent preparation436/169With reagent in absorbent or bibulous substrate
ExaminersPrimary: Kepplinger, Esther M.
Assistant: Spiegel, Carol A.
Attorney, Agent or Firm
Foreign Patent References
International ClassesC12Q 001/54
AbstractA method for determining the presence of an analyte in a fluid is described along with various components of an apparatus specifically designed to carry out the method. The method involves taking a reflectance reading from one surface of an inert porous matrix impregnated with a reagent that will interact with the analyte to produce a light-absorbing reaction product when the fluid being analyzed is applied to another surface and migrates through the matrix to the surface being read. Reflectance measurements are made at two separate wavelengths in order to eliminate interferences, and a timing circuit is triggered by an initial decrease in reflectance by the wetting of the surface whose reflectance is being measured by the fluid which passes through the inert matrix. The method and apparatus are particularly suitable for the measurement of glucose levels in blood without requiring separation of red blood cells from serum or plasma.
Field of SearchMEASURING OR TESTING PROCESS INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITION OR TEST STRIP THEREFORE; PROCESSES OF FORMING SUCH COMPOSITION OR TEST STRIP
Involving glucose or galactose
OPTICAL SENSING APPARATUS
PACKAGED DEVICE OR KIT
Wine or alcoholic beverages
With sample on test slide
BIOLOGICAL CELLULAR MATERIAL TESTED
Including reagent preparation
With reagent in absorbent or bibulous substrate
Having reagent in absorbent or bibulous substrate
Having coated reagent
In holder or container having special form
Test package or kit