U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Menthol enhancement of transdermal drug delivery

Patent 4933184 Issued on June 12, 1990. Estimated Expiration Date: Icon_subject June 12, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3880996

3891757

Sympathomimetic topical and percutaneous administration with halogenated promoters
Patent #: 3968245
Issued on: 07/06/1976
Inventor: Higuchi

Vehicle composition containing 1-substituted azacycloheptan-2-ones
Patent #: 3989816
Issued on: 11/02/1976
Inventor: Rajadhyaksha

Coal tar gel composition
Patent #: 4178373
Issued on: 12/11/1979
Inventor: Klein ,   et al.

Therapeutic composition
Patent #: 4261982
Issued on: 04/14/1981
Inventor: Luedders ,   et al.

Composition for topical application and method for preparing the same
Patent #: 4316887
Issued on: 02/23/1982
Inventor: Kamishita ,   et al.

Penetrating topical medicament
Patent #: 4353896
Issued on: 10/12/1982
Inventor: Levy

Transdermal carrier materials
Patent #: 4362737
Issued on: 12/07/1982
Inventor: Schafer ,   et al.

Penetration enhancers for transdermal drug delivery of systemic agents
Patent #: 4405616
Issued on: 09/20/1983
Inventor: Rajadhyaksha

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Inventor

Assignee

Application

No. 034803 filed on 04/03/1987

US Classes:

424/449, Transdermal or percutaneous514/946, PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED)514/947Topical application

Examiners

Primary: Rose, Shep K.

Attorney, Agent or Firm

Foreign Patent References

  • 83/03548 WO. 10/13/1983

International Classes

A61K 009/06
A61F 013/00
A61L 015/03

Abstract

Disclosed herein are compositions and methods for enhancing the transdermal delivery of physiologically active agents across mammalian skin or membranes and which comprise a percutaneous transfer enhancing amount of menthol and a drug.

Other References

  • Martindale Extra Pharmacopoeia 28th Ed. (1982) pp. 672, 673, 675, 351-352 "Cajuput Oil" Cineole Eucalyptus Oil Camphor and Menthol
  • Derwent Abstract of JPN 58004713 (1/83) Yugioku Yakohin Koey
  • Derwent Abstract of Ger. Off. 3231400 (3/83) Kawamura Inst. (Aurika
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