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Visible fluorescence spectral diagnostic for laser angiosurgery Patent #: 4718417
ApplicationNo. 186747 filed on 04/25/1988
US Classes:600/477, With comparison means (e.g., ratio of or comparison to a standard)600/478, Light conducting fiber inserted into a body607/901CANCER DETECTION
ExaminersPrimary: Smith, Ruth S.
Attorney, Agent or Firm
Foreign Patent References
International ClassA61B 005/00
AbstractA method and apparatus for detecting the presence of cancerous tissue using visible luminescence. The tissue to be examined is excited with a beam of monochromatic light that causes the tissue to fluoresce over a spectrum of wavelengths. The intensity at which the excited tissue fluoresces can be measured either over a spectrum or at a predetermined number of preselected wavelengths. By determining the wavelength(s) at which maximum intensity(ies) are attained for the tissue in question and by comparing these peak wavelengths, either visually or electronically, to the peak wavelength(s) derived from a known non-cancerous tissue, or by comparing the spectrum of the excited tissue with the spectrum of a known noncancerous tissue one can determine the carcinomatoid status of the tissue in question. The invention is based on the discovery that the visible luminescence spectra for cancerous and non-cancerous tissue are substantially different and that the differences are such that visible luminescence from tissue can be used to detect the presence of cancer.
Field of SearchWith plural detectors (e.g., simultaneous viewing)