N-homocysteine thiolactonyl retinamido cobalamin and methods of use thereof
Patent 4925931 Issued on May 15, 1990. Estimated Expiration Date: 
July 14, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 14, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesHomocysteine thiolactone perchlorate as a tumor promotor Derivatives of coenzyme B12 Homocysteine thiolactone salts and use thereof as anti-neoplastic agents Vitamin B12 and labelled derivatives for such assay N-homocysteine thiolactonyl retinamide and use thereof as an antineoplastic agent Patent #: 4618685 InventorApplicationNo. 219499 filed on 07/14/1988US Classes:536/26.4, Cobalamin nucleotides (e.g., vitamin B-12, etc.)435/86, Cobalamin (i.e., vitamin B12, LLD factor)514/52, Phosphorus containing (e.g., Vitamin B12, etc.)536/26.41, Processes of preparing or labelling536/26.44, Cobalamin analogs (i.e., compounds wherein the benzimidazole ring system has been replaced by another organic ring structure, or compounds wherein cobalt has been removed or replaced by another metal, or is substituted by a group other than -OH or -CN)549/29The hetero ring is five-memberedExaminersPrimary: Brown, Johnnie R.Assistant: Kunz, Gary L. Attorney, Agent or FirmInternational ClassesC07H 019/167C07D 333/20 A61K 031/365 A61K 031/38 AbstractN-Homocysteine thiolactonyl retinamido cobalamin is useful for decreasing the induction of chemically-induced tumors in animals. It is also useful for inhibiting weight gain.Other References
|
| ||||||||||||||
