Radio frequency plasma deposited polymers that enhance cell growth
December 21, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3853712 3910819 Roller culture bottle insert Cell culture method Cell culture method Roller bottle Soft corneal contact lens with tightly cross-linked polymer coating and method of making same Method for manufacturing a roller bottle Microparticles, preparation thereof and applications thereof in biology, particularly in the culture of human diploid cells Patent #: 4373027 InventorsAssigneeApplicationNo. 136457 filed on 12/21/1987US Classes:427/2.25, Liquid conveying (e.g., vascular, arterial, bile duct, urethra)427/2.24, Implantable permanent prosthesis (i.e., artificial body member) (e.g., pacemaker, lens, cornea, glaucoma shunt, heart valve, muscle, spinal disc, breast, internal organ)427/491, Organic substrate435/176, Enzyme or microbial cell is immobilized on or in an inorganic carrier435/402, Support is a coated or treated surface623/921Blood vesselExaminersPrimary: Lusignan, Michael R.Attorney, Agent or FirmForeign Patent References
International ClassA61F 002/06AbstractA method for enhancing bio-material capability for use as a supporting surface for cell culture is disclosed. The method requires exposure of the bio-material to a plasma polymerizable polymer gas, which includes oxygen-containing organic molecules. The material surfaces are then subjected to an RF plasma gas discharge in the presence of the gas, causing a deposition on the exposed material surfaces of a conformal overcoating of the polymer on the material. The deposition enhances fibronectin adsorption and hence cell attachment, spreading and cell growth. Preferred polymerizable gases are acetone, methanol, and ethylene oxide.Other References
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