InventorAssigneeApplicationNo. 371161 filed on 06/26/1989US Classes:514/91, Hetero ring is five-membered514/422, Additional hetero ring514/423C=X bonded directly to the five-membered hetero ring by nonionic bonding (X is chalcogen)ExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassesA61K 031/40A61K 031/675 AbstractA method is provided for inhibiting onset of or treating depression by administering an ACE inhibitor, which is (S)-1-[6-amino-2-[[hydroxy-(4-phenylbutyl)phosphenyl]oxy]-1-oxohexyl]-L-pr oline, fosinopril or zofenopril, alone or in combination with an antidepressant drug such as lithium, over a prolonged period of treatment.Other References
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