U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Sustained release, comfort formulation for glaucoma therapy

Patent 4911920 Issued on March 27, 1990. Estimated Expiration Date: Icon_subject February 5, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3867519

Structured bioerodible drug delivery device
Patent #: 3962414
Issued on: 06/08/1976
Inventor: Michaels

Polystyrene sulfonate containing opthalmic solutions
Patent #: 3987163
Issued on: 10/19/1976
Inventor: Rankin

Method of treatment for glaucoma
Patent #: 4127674
Issued on: 11/28/1978
Inventor: Leopold

Drug-dispensing device and method
Patent #: 4207890
Issued on: 06/17/1980
Inventor: Mamajek ,   et al.

Sustained release ophthalmic drug dosage
Patent #: 4271143
Issued on: 06/02/1981
Inventor: Schoenwald ,   et al.

Sustained release ophthalmic drug dosage
Patent #: 4407792
Issued on: 10/04/1983
Inventor: Schoenwald ,   et al.

Microcapsules and method of preparing same
Patent #: 4462982
Issued on: 07/31/1984
Inventor: Samejima ,   et al.

Ophthalmic compositions and their use for treating elevated intraocular pressure and glaucoma Patent #: 4521414
Issued on: 06/04/1985
Inventor: Chiou ,   et al.

Inventors

Application

No. 154514 filed on 02/05/1988

US Classes:

424/78.04, Ophthalmic preparation424/78.1, Ion exchange resin424/501, Contains solid synthetic resin514/913Glaucoma

Examiners

Primary: Rose, Shep K.
Assistant: Fay, Zohreh

Attorney, Agent or Firm

International Class

A61K 031/78

Abstract

Disclosed are nonstinging, sustained release ophthalmic formulations to control intraocular pressure in antiglaucoma therapy comprising a basic active, a cation exchange resin, and, inter alia, an acidic, mucomimetic polymer. Also disclosed are methods of treatment comprising administering such formulations topically to the eye when indicated for control and lowering of intraocular pressure.

Other References

  • Chem. Abst. 98:210936j (1983) Heath et a
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