U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Diffusion matrix for transdermal drug administration and transdermal drug delivery devices including same

Patent 4911916 Issued on March 27, 1990. Estimated Expiration Date: Icon_subject April 8, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3426754

3486968

3645835

3685734

3699963

3849238

Therapeutic system for administering drugs to the skin
Patent #: 4286592
Issued on: 09/01/1981
Inventor: Chandrasekaran

Skin barrier
Patent #: 4367732
Issued on: 01/11/1983
Inventor: Poulsen ,   et al.

Dosage for coadministering drug and percutaneous absorption enhancer
Patent #: 4379454
Issued on: 04/12/1983
Inventor: Campbell ,   et al.

Polymeric diffusion matrix containing estrogens
Patent #: 4438139
Issued on: 03/20/1984
Inventor: Keith ,   et al.

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Inventor

Assignee

Application

No. 179561 filed on 04/08/1988

US Classes:

424/449, Transdermal or percutaneous424/447, Bandages with incorporated medicaments424/448Pressure sensitive adhesive means

Examiners

Primary: Page, Thurman K.
Assistant: Prater, P. L.

Attorney, Agent or Firm

Foreign Patent References

  • 0196769 EP. 10/13/1988

International Class

A61F 013/00

Foreign Application Priority Data

1987-12-14 AU

Abstract

A solid state, resilient laminated composite for administering a drug transdermally consisting of a top layer of a resilient elastomer; a middle diffusion matrix layer composed of a polyurethane macroporous foam framework in whose pores are embedded a viscoelastic blend of a medical grade polysiloxane adhesive, drug, and optionally a percutaneous absorption enhancer, and a basal surface layer of the medical grade polysiloxane adhesive.

Other References

  • A. S. Michaels, S. K. Chandrasekaran and J. E. Shaw-Drug Permeation Through Human Skin: Theory and in Vitro Experimental Measurement
  • Y. W. Chien-Novel Drug Delivery Systems-Fundamentals, Development-Concepts, Biomedical Assessment
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