U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Electrophoresis apparatus

Patent 4911817 Issued on March 27, 1990. Estimated Expiration Date: Icon_subject October 20, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Electrophoresis using alternating transverse electric fields
Patent #: 4473452
Issued on: 09/25/1984
Inventor: Cantor ,   et al.

Cellular spin resonance spectrometer
Patent #: 4569741
Issued on: 02/11/1986
Inventor: Pohl

Methods for immobilizing and translocating biological cells
Patent #: 4661451
Issued on: 04/28/1987
Inventor: Hansen

Field-inversion gel electrophoresis
Patent #: 4737251
Issued on: 04/12/1988
Inventor: Carle ,   et al.

Pulsed-field gradient gel electrophoretic apparatus Patent #: 4740283
Issued on: 04/26/1988
Inventor: Laas ,   et al.

Inventor

Application

No. 260150 filed on 10/20/1988

US Classes:

204/607, With control means responsive to sensed condition204/609Plural rapid changes in direction of electric field (at least 1,000 times total and at more than 1/sec) (e.g., pulsed field, etc.)

Examiners

Primary: Niebling, John F.
Assistant: Ryser, David G.

Attorney, Agent or Firm

International Class

B01D 013/02

Abstract

In an apparatus for electrophoresis, using a support for a gel and a liquid buffer, a plurality of driving electrodes arrayed in spaced relation to one another so as to contact the medium, and a plurality of sensing electrodes arrayed in spaced relation to one another and the driving electrodes so as to contact the medium. Each sensing electrode is preferably radially inward of and paired with a single one of the driving electrodes. Means are provided respectively for providing electrical potentials to be applied to selected ones of the driving electrodes, for applying the provided potentials, for sensing electrical potentials at selected ones of the sensing electrodes, and for adjusting the applied potentials to maintain the sensed potential at a selected value at a sensing electrode of each pair. The apparatus may be programmably controllable so as to enable an electric field to be modulated in amplitude and direction, as a function of time.

Other References

  • Biotechnology, Dec. 1986, p. 1054, "Tricks Tame Megabase DNA Fragments", Douglas McCormick
  • Science, vol. 234, Dec. 19, 1986, pp. 1582-1585, "Separation of Large DNA Molecules . . . Fields", Gilbert Chu et al
  • Nucleic Acids Research, vol. 16, No. 15, Aug. 11, 1988, pp. 7563-7582, "Optimized Conditions". . . of DNA, Bruce W. Birren et a
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