Use of demineralized bone matrix in the repair of segmental defects
Patent 4902296 Issued on February 20, 1990. Estimated Expiration Date: 
October 29, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
October 29, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesBone morphogenetic protein process Element for implantation in body tissue, particularly bone tissue Process for producing antithrombogenic vinyl acetate polymer or hydrolyzate thereof Method of inducing osseous formation by implanting bone graft material Patent #: 4472840 InventorsAssigneeApplicationNo. 114002 filed on 10/29/1987US Classes:623/23.63, Including natural bone tissue427/2.14, Particulate or unit-dosage-article base (e.g., tablet, pill, pellet, capsule, liposome, powder, controlled-release implant, suppository; excluding transdermal patch)427/2.26, For mineralized body part (e.g., bone, tooth, crown, hip)514/21, Produced by or extracted from animal tissue530/840Bones; tendons; teeth; cartilageExaminersPrimary: Cannon, Alan W.Attorney, Agent or FirmInternational ClassesA61F 002/28A61K 035/12 A01N 001/02 AbstractA grafting material comprising milled bone which has an initial coating of guanidine-extracted bone proteins which are dialyzed from solution. Unbound bone proteins are removed and this augmented milled bone is lyophized. A subsequent coat of anti-coagulated plasma containing plasma proteins is applied to the augmented milled bone. The unbound plasma proteins are removed from the coating by rinsing. |
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