Treatment of colic and teething

Patent 4889850 Issued on December 26, 1989. Estimated Expiration Date:

December 28, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

2899436

3109843

3136815

3371085

Medicament Patent #: 4734412
Issued on: 03/29/1988
Inventor: Kessler

Inventors

Application

No. 291475 filed on 12/28/1988

US Classes:

514/221, Bicyclo ring system having the seven-membered hetero ring as one of the cyclos514/255.04Plural carbocyclic rings bonded directly to the same acyclic carbon atom which is attached directly or indirectly to the piperazine ring by nonionic bonding

Examiners

Primary: Friedman, Stanley J.
Assistant: Fay, Zohreh

Attorney, Agent or Firm

Townsend and Townsend

International Classes

A61K 031/55
A61K 031/495

Abstract

Teething and colic are alleviated in infants and toddlers by the administration of a combination of an antihistamine and a benzodiazepine having sedative hypnotic activity. An exemplary antihistamine is hydroxyzine pamoate, and an exemplary benzodiazepine is diazepam.

Other References

J. M. Clifford, "Determination of Two Benzodiazepine Anticonvulsants In The Plasma . . .", Methodol. Dev. Biochem., 1976, vol. 5, pp. 203-209
E. Czarnecka et al., "Polish Soc. of Electroencephalography and Clinical Neurophysiology", (Neth.), 1987, vol. 45(3), pp. 7P-8