Patent References 2897202 N-substituted-17ଲ-carbamoylandrost-4-en-3-one 5 reductase inhibitors Preparation of 4-aza-17-substituted-5-androstan-3-ones useful as 5-reductase inhibitors Novel steroid 5-reductase inhibitors 4-Aza-17ଲ-substituted-5-androstan-3-one-reductase inhibitors Steroidic 5-reductase inhibitors 17ଲ-N-monosubstituted carbamoyl-4-aza-5-androst-1-en-3-ones which are active as testosterone 5-reductase inhibitors Patent #: 4760071 InventorsApplicationNo. 007539 filed on 07/28/1987US Classes:514/278, Spiro ring system514/284, Tetracyclo ring system having the six-membered hetero ring as one of the cyclos514/859, Acne546/16, The spiro includes the six-membered hetero ring546/77, The six-membered hetero ring shares ring members with one other cyclo only546/78Plural chalcogens bonded directly to carbocyclic rings of the tetracyclo ring system (e.g., pyridoanthraquinones, etc.)ExaminersPrimary: Shah, Mukund J.Assistant: Rozycki, Andrew G. Attorney, Agent or FirmInternational ClassesA61K 031/58C07J 073/00 AbstractInvented are 4-aza-5-alpha-8(14)-17 substituted-androsten-3-ones having an 8(14), 7(8), or 16(17) double bond, optionally also having a 1(2) double bond, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5-alpha-reductase.Other References
Field of SearchThe six-membered hetero ring shares ring members with one other cyclo onlyPlural chalcogens bonded directly to carbocyclic rings of the tetracyclo ring system (e.g., pyridoanthraquinones, etc.) The spiro includes the six-membered hetero ring Tetracyclo ring system having the six-membered hetero ring as one of the cyclos Spiro ring system |
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