Patent ReferencesMedical bandage Microsealed pharmaceutical delivery device Polymeric diffusion matrix containing estradiol diacetate Water absorptive composition Transdermal nitroglycerin pad Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer Microphase separated hydrogels for controlled release of bioactive materials Patent #: 4693887 InventorsApplicationNo. 868709 filed on 05/30/1986US Classes:424/448, Pressure sensitive adhesive means424/449, Transdermal or percutaneous424/486Synthetic polymerExaminersPrimary: Page, Thurman K.Assistant: Horne, Leon R. Attorney, Agent or FirmInternational ClassA61F 013/02AbstractThis invention relates to a novel transdermal absorption dosage unit comprising a backing layer, an adjoining layer of solid polymer matrix in which estradiol or another steroidal pharmaceutical having estrogenic activity is microdispersed; and a biologically acceptable adhesive means by which the dosage unit adheres to the skin of the subject being administered said estradiol or another said steroidal pharmaceutical and adapted to permit transdermal absorption of said estradiol or another said steroidal pharmaceutical. Additionally, the invention relates to improved estradiol or other estrogenic steroid maintenance therapy. | |