U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Transdermal absorption dosage unit for estradiol and other estrogenic steroids and process for administration

Patent 4883669 Issued on November 28, 1989. Estimated Expiration Date: Icon_subject November 28, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Medical bandage
Patent #: 3996934
Issued on: 12/14/1976
Inventor: Zaffaroni

Microsealed pharmaceutical delivery device
Patent #: 4053580
Issued on: 10/11/1977
Inventor: Chien ,   et al.

Polymeric diffusion matrix containing estradiol diacetate
Patent #: 4291014
Issued on: 09/22/1981
Inventor: Keith ,   et al.

Water absorptive composition
Patent #: 4300820
Issued on: 11/17/1981
Inventor: Shah

Transdermal nitroglycerin pad
Patent #: 4336243
Issued on: 06/22/1982
Inventor: Sanvordeker ,   et al.

Percutaneous absorption enhancer dispenser for use in coadministering drug and percutaneous absorption enhancer
Patent #: 4460372
Issued on: 07/17/1984
Inventor: Campbell ,   et al.

Microphase separated hydrogels for controlled release of bioactive materials Patent #: 4693887
Issued on: 09/15/1987
Inventor: Shah

Inventors

Application

No. 868709 filed on 05/30/1986

US Classes:

424/448, Pressure sensitive adhesive means424/449, Transdermal or percutaneous424/486Synthetic polymer

Examiners

Primary: Page, Thurman K.
Assistant: Horne, Leon R.

Attorney, Agent or Firm

International Class

A61F 013/02

Abstract

This invention relates to a novel transdermal absorption dosage unit comprising a backing layer, an adjoining layer of solid polymer matrix in which estradiol or another steroidal pharmaceutical having estrogenic activity is microdispersed; and a biologically acceptable adhesive means by which the dosage unit adheres to the skin of the subject being administered said estradiol or another said steroidal pharmaceutical and adapted to permit transdermal absorption of said estradiol or another said steroidal pharmaceutical. Additionally, the invention relates to improved estradiol or other estrogenic steroid maintenance therapy.

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