Controlled drug delivery system for treatment of neural disorders
April 29, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3625214 3832252 3880991 Novel drug delivery device Controlled drug releasing preparations Methods of improving control of release rates and products useful in same Drug-delivery device comprising certain polymeric materials for controlled release of drug Osmotic bursting drug delivery device System with microporous reservoir having surface for diffusional delivery of agent Pharmaceutical preparation comprising a cardiac glycoside with a polymer coating InventorsApplicationNo. 043695 filed on 04/29/1987US Classes:424/422, Implant or insert424/423, Surgical implant or material424/425, Diffusion barrier is matrix424/426, Errodable, resorbable, or dissolving424/486, Synthetic polymer424/487Acrylic acid and derivativesExaminersPrimary: Page, Thurman K.Attorney, Agent or FirmForeign Patent References
International ClassesA61F 013/00A61K 009/14 AbstractThe present invention is a method and composition for treatment of ischemic, metabolic, congenital, or degenerative disorders of the central or peripheral nervous system. The composition is formed by encapsulation within an implantable biocompatible polymeric device of one or more compounds which have the effect or replacing or stimulating functions of the nervous system. A variety of biocompatible polymers including both biodegradable and non-degradable polymers can be used to form the implants. An essential feature of the composition is linear release, achieved through manipulation of the polymer composition and form. The selection of the shape, size, drug, polymer, and method for implantation are determined on an individual basis according to the disorder to be treated and the individual patient response. A plethora of neurally active substances can be used to treat or manipulate neurological disorders, including Parkinson's Disease, particularly the subset which is refractory or poorly responsive to existing therapies; Alzheimer's Disease; Huntington's Disease; and trauma, such as spinal cord injury.Other References
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