Cyclophosphamide
Patent 4879286 Issued on November 7, 1989. Estimated Expiration Date: 
April 4, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
April 4, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3018302 3732340 Lyophilized cyclophosphamide Patent #: 4537883 InventorsAssigneeApplicationNo. 178761 filed on 04/04/1988US Classes:514/110Phosphorus is part of a ringExaminersPrimary: Goldberg, Jerome D.Attorney, Agent or FirmForeign Patent References
International ClassA61K 031/66AbstractA storage-stable liquid oncolytic formulation of cyclophosphamide for parenteral administration is presented. Currently utilized lyophilized formulations have inherent diseconomies and increased hazard is associated with reconstitution. The liquid formulations of the present invention comprise a solution of cyclophosphamide with an organic polyol as cosolvent, which provide enhanced shelf-life and greater ease of administration. The polyol is either propylene glycol, polyethylene glycol or glyerol. The solution of cyclophosphamide is either aqueous, or in the case of propylene glycol may constitute 10-30% by weight of an alcohol.Field of SearchPhosphorus is part of a ring | |
