Patent References 3873576 Preparation of optically active trans-hexahydrodibenzopyranones Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor Hexahydro-1-hydroxy-9-hydroxymethyl-3-substituted-6H-dibenzo[b,d]pyrans as analgesic agents Novel tetrahydrocannabinol type compounds Patent #: 4179517 InventorsApplicationNo. 112705 filed on 10/26/1987US Classes:514/454, Tricyclo ring system having the hetero ring as one of the cyclos549/390, Dibenzo(b,d)pyrans (including hydrogenated)549/391Plural chalcogens bonded directly to the tricyclo ring systemExaminersPrimary: Chan, NickyAttorney, Agent or FirmInternational ClassesA61K 031/35C07D 311/80 Foreign Application Priority Data1986-10-24 ILAbstractThe invention relates to novel (3S,4S)-7-hydroxy-Ɗ6 -tetrahydrocannabinol homologes and derivatives, essentially free of the (3R,4R) form and to pharmaceutical compositions which have a potent analgetic, antiemetic and antiglaucoma effect, which compositions contain an effective dosage of a compound of this type. The novel pharmaceutical compositions are practically devoid of the undesired side effects of the (3R,4R) type compounds, such as cannabimimetic psychotropic effects. The pharmaceutical compositions are of special utility in cases of acute and of chronic pain. The invention also relates to a process for the production of the above defined novel compounds.Other References
|
| ||||||||||||||