Percutaneous absorption preparation
March 26, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesCompositions for topical application to animal tissue and method of enhancing penetration thereof Antiinflammatory analgesic gelled ointment Preparation and method for the treatment of acne Gel-like ointment containing indometacin Gel preparations for external application Pharmaceutical preparations Method for percutaneously administering physiologically active agents Patent #: 4710497 InventorAssigneeApplicationNo. 031241 filed on 03/26/1987US Classes:424/46, Powder or dust containing514/128, Sulfur bonded directly to a benzene ring514/220, Tricyclo ring system having the seven-membered hetero ring as one of the cyclos514/419, C=X bonded directly or indirectly by an acyclic carbon or carbon chain to ring carbon of the five-membered hetero ring (e.g., tryptophan, etc.) (X is chalcogen)514/420, Indomethacine per se or ester thereof514/946, PENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED)514/947Topical applicationExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmForeign Patent References
International ClassesA61K 031/40A61K 031/54 A61K 031/78 Foreign Application Priority Data1986-05-07 JPAbstractA percutaneous absorption preparation which comprises calcium salt of an acidic anti-inflammatory or analgesic drug having carboxyl group as the active ingredient and present in an amount of 0.3-10% by weight; a medium for the active ingredient which is selected form the group consisting of an ethylene glycol mono-lower alkyl ether, propylene glycol, polyethylene glycol and dimethylsulfoxide, the medium being present in an amount at least sufficient to dissolve the active ingredient; an absorption promotor selected from the group consisting of 1-dodecylazacycloheptan-2-one, hexamethylenelauramide, N-methyl-2-pyrrolidone, a sucrose aliphatic acid ester, dimethylsulfoxide and a nonionic surfactant and present in an amount of 0.5-10% by weight; and the remaining being other reagents and/or carriers required for a desired form of the preparation.Field of SearchTricyclo ring system having the seven-membered hetero ring as one of the cyclosPENETRANT OR ABSORBENT (ENHANCES PENETRATION INTO SUBJECT TREATED) Topical application C=X bonded directly or indirectly by an acyclic carbon or carbon chain to ring carbon of the five-membered hetero ring (e.g., tryptophan, etc.) (X is chalcogen) Indomethacine per se or ester thereof | |
