Tablet for pharmaceutical use able to release active substances at successive times
Patent 4865849 Issued on September 12, 1989. Estimated Expiration Date: 
December 30, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
December 30, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3317394 Process for the manufacture of a multi-zone tablet and tablet manufactured by this process Coating ensuring a controlled release of active ingredients of biologically active compositions, particularly pharmaceutical compositions and a process for preparation of biologically active compositions ensuring controlled release of active ingredients Sorbitol coated comestible and method of preparation Controlled release formulation Patent #: 4756911 InventorsAssigneeApplicationNo. 07/139635 filed on 12/30/1987US Classes:424/466, Effervescent424/470, Where particles are granulated424/471, Plural concentric cores424/472, Layered unitary dosage forms424/480, Cellulose or derivative424/482Containing solid synthetic polymersExaminersPrimary: Page, Thurman K.Attorney, Agent or FirmInternational ClassesA61K 9/20 (20060101)A61K 9/24 (20060101) Foreign Application Priority Data1987-01-13 ITAbstractA tablet for pharmaceutical use able to release active substances at successive times, comprising at least; a first layer containing a portion of the active substance with suitable excipients, a barrier layer of polymer material gellable and/or soluble in water and/or aqueous liquids, which is interposed between said first layer and a third layer containing the remaining portion of active substance with suitable excipients, said barrier layer and said third layer being housed in a casing consisting of polymer material impermeable and insoluble in water or soluble in an alkaline environment.That part of the active substance not inserted in the casing is immediately available for dissolving, whereas the part inserted in the casing is available only after dissolution or rupture of the barrier layer and/or after solubilization of the casing. | |
