U.S. patents available from 1976 to present.
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Process for obtaining proanthocyanidine A2, pharmaceutical compositions and their therapeutic use

Patent 4863956 Issued on September 5, 1989. Estimated Expiration Date: Icon_subject September 5, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Pharmaceutical compositions Patent #: 4258055
Issued on: 03/24/1981
Inventor: Lietti ,   et al.

Inventors

Assignee

Application

No. 06/886790 filed on 07/18/1986

US Classes:

514/453, Polycyclo ring system having the hetero ring as one of the cyclos514/926, Duodenal514/927Peptic

Examiners

Primary: Waddell, Frederick E.

Attorney, Agent or Firm

International Classes

C07D 493/18 (20060101)
C07D 493/00 (20060101)

Foreign Application Priority Data

1985-07-19 GB

Abstract

There is described a process for preparing proanthocyanidine A2 by extraction from cortex or fruits of Aesculus hippocastanum and related species and its activity for stimulating healing processes, e.g. healing wounds and injuries of various origins, gastric and duodenal ulcers for modifying conditions of impaired capillary permeability and resistance and for obtaining an anti-lipid peroxidation effect.There are also described pharmaceutical formulations suitable for use by topical and systemic routes.

Other References

  • Tetrahedron Lett., 429, 1966
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