Patent ReferencesOximes of oxymorphone, naltrexone and naloxone as potent, selective opioid receptor agonists and antagonists Patent #: 4760069 InventorsAssigneeApplicationNo. 07/293196 filed on 01/04/1989US Classes:514/282One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.)ExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassA61K 31/485 (20060101)AbstractA method of treating a human or animal patient suffering from an arthritic disease or associated inflammatory disease comprises daily administration to such patient of from about 1 to about 100 mg of the narcotic antagonists nalmefene or naltrexone. The nalmefene or naltrexone may be administered in equally divided doses from one to four times daily, preferably by the oral route. Parental administration may be utilized where suitable.Other References
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