Amino acid chelated compositions for delivery to specific biological tissue sites
Patent 4863898 Issued on September 5, 1989. Estimated Expiration Date: 
September 5, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
September 5, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3887704 Increasing metals in biological tissue Biological assimilation of metals Buffered enzymatically produced metal proteinates Pure amino acid chelates Patent #: 4599152 InventorsAssigneeApplicationNo. 06/826786 filed on 02/06/1986US Classes:514/6, Heavy metal containing (e.g., hemoglobin, etc.)514/18, 3 or 4 peptide repeating units in known peptide chain514/19, 2 peptide repeating units in known peptide chain514/21, Produced by or extracted from animal tissue514/399, Chalcogen or nitrogen bonded indirectly to the imidazole ring by nonionic bonding514/419, C=X bonded directly or indirectly by an acyclic carbon or carbon chain to ring carbon of the five-membered hetero ring (e.g., tryptophan, etc.) (X is chalcogen)514/428, Chalcogen bonded indirectly to the five-membered hetero ring by acyclic nonionic bonding514/492, Heavy metal containing DOAI514/494, Zinc514/499, Copper514/500, With an additional active ingredient514/501, Nickel or cobalt514/502, Iron514/505, Cadmium or chromium514/880, HAIR TREATMENT (THERAPEUTIC-SCALP)514/891, KIDNEY STONE514/893LIVER DISORDERExaminersPrimary: Schain, Howard E.Assistant: Moezie, F. T. Attorney, Agent or FirmInternational ClassesA61K 38/04 (20060101)A61K 31/195 (20060101) A61K 31/185 (20060101) AbstractAmino acid chelates having a ligand to divalent metal mole ratio of at least 2:1 and having a molecular weight of not more than 1500 and preferably not more than 1000 and also having a stability constant of between about 10 and 10 are formulated for delivery to one or more specific tissue sites within a mammal. The ligand utilized in formulating the amino acid chelate is a naturally occuring amino acid or a dipeptide, tripeptide or quadrapeptide thereof. The selection of an appropriate ligand with which to form the chelate provides a product that, when entering the bloodstream of the mammal, either by mean of oral ingestion or injection, has a propensity to migrate to one or more targeted tissue sites within the mammal.Other References
Field of SearchZincHeavy metal containing (e.g., hemoglobin, etc.) 3 or 4 peptide repeating units in known peptide chain 2 peptide repeating units in known peptide chain HAIR TREATMENT (THERAPEUTIC-SCALP) LIVER DISORDER KIDNEY STONE C=X bonded directly or indirectly by an acyclic carbon or carbon chain to ring carbon of the five-membered hetero ring (e.g., tryptophan, etc.) (X is chalcogen) Chalcogen bonded indirectly to the five-membered hetero ring by acyclic nonionic bonding | |
