Ophthalmological composition of the type which undergoes liquid-gel phase transition

Patent 4861760 Issued on August 29, 1989. Estimated Expiration Date:

September 25, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

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Inventors

Assignee

Merck & Co., Inc.

Application

No. 06/911606 filed on 09/25/1986

US Classes:

514/54, Polysaccharide514/912, OPHTHALMIC514/913, Glaucoma514/915, Wetting agent514/944, GEL536/114, Gums or derivatives536/123Plural diverse saccharides containing (e.g., hetero polysaccharides, etc.)

Examiners

Primary: Griffin, Ronald W.
Assistant: Carson, Nancy S.

Attorney, Agent or Firm

International Classes

A61K 9/00 (20060101)
C12P 19/00 (20060101)
C12P 19/04 (20060101)
A61K 47/36 (20060101)

Foreign Application Priority Data

1985-10-03 FR

Abstract

The present invention relates to a pharmaceutical composition intended for contacting with a physiological liquid characterized in that said composition is intended to be administered as a non-gelled liquid form and is intended to gel in situ, this composition containing at least one polysaccharide in aqueous solution, of the type which undergoes liquid-gel phase transition gelling in situ under the effect of an increase in the ionic strength of said physiological liquid.