Novel class of acyl-derivatives of carnitine, process for preparing same and therapeutic use thereof
Patent 4859698 Issued on August 22, 1989. Estimated Expiration Date: 
May 31, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
May 31, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesNovel thiolane-2,4-dione-3-carboxamide fungicides Certain sulfonyl carbamate on thiocarbamate intermediates Anticonvulsant γ-thiobutyrolactone derivatives Patent #: 4707491 InventorsAssigneeApplicationNo. 07/200641 filed on 05/31/1988US Classes:514/445, Chalcogen bonded directly to ring carbon of the hetero ring514/446, Chalcogen bonded directly to ring sulfur by nonionic bonding514/448, C=O bonded directly to the hetero ring (X is chalcogen)549/64, Having -C(=X)-, wherein X is chalcogen, bonded directly to the hetero ring549/65, Nitrogen attached indirectly to the hetero ring by nonionic bonding549/71, The -C(=X)- is part of a -C(=X)X- group, wherein the X's are the same or diverse chalcogens549/72Nitrogen or chalcogen attached indirectly to the hetero ring by nonionic bondingExaminersPrimary: Raymond, Richard L.Assistant: Covington, Raymond Attorney, Agent or FirmInternational ClassesA61K 31/195 (20060101)A61K 31/14 (20060101) A61K 31/215 (20060101) A61K 31/185 (20060101) A61K 31/21 (20060101) A61K 31/205 (20060101) A61K 31/38 (20060101) C07D 333/38 (20060101) C07D 333/22 (20060101) C07D 333/32 (20060101) C07D 333/24 (20060101) C07D 339/00 (20060101) C07D 339/02 (20060101) C07D 339/04 (20060101) C07D 333/00 (20060101) Foreign Application Priority Data1980-03-06 ITAbstractA novel class of acyl-derivatives of carnitine is disclosed wherein the acyl radical is either the radical of unsaturated organic acids (typically, acrylic acid) or the radical of saturated organic acids substituted with tert-alkyl, cycloalkyl, cycloalkenyl, alkoxyl, heterocyclic and carboalkoxylradicals, or with aldehyde or hydroxy groups. These acyl-derivatives of carnitine are useful therapeutical agents in the treatment of cardiac disorders, hyperlipidaemias and hyperlipoproteinaemias. |
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