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Method of treatment for autoimmune diseases

Patent 4857533 Issued on August 15, 1989. Estimated Expiration Date: Icon_subject December 15, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Inventors

Assignee

Application

No. 07/284615 filed on 12/15/1988

US Classes:

514/282One of the five cyclos is five-membered and includes ring chalcogen (e.g., codeine, morphine, etc.)

Examiners

Primary: Friedman, Stanley J.

Attorney, Agent or Firm

International Class

A61K 31/485 (20060101)

Abstract

A method of treating a human or animal patient suffering from an autoimmune disease comprises daily administration to such patient of from about 1 to about 100 mg of the narcotic antagonists nalmefene or naltrexone. The nalmefene or naltrexone may be administered in equally divided doses from one to four times daily, preferably by the oral route. Parenteral administration may be utilized where suitable.

Other References

  • Chem. Abst. 100 (1984)-80084b-1
  • Chem. Abst. 108 (1988)-143338a
  • Rios et al., Eur. J. Pharm., 96:277-289 (1983)
  • Kayser et al., Proceedings of the Vth World Congress on Pain, pp. 72-79 (Elsevier Science Publishers 1988)
  • Hargreaves et al., Proceedings of the Vth World Congress on Pain, pp. 55-60 (Elsevier Science Publishers 1988)
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