Computer-based method for designing stablized proteins

Patent 4853871 Issued on August 1, 1989. Estimated Expiration Date:

April 6, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

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Inventors

Assignee

Genex Corporation

Application

No. 07/034966 filed on 04/06/1987

US Classes:

701/99, With indicator or control of power plant (e.g., performance)436/89, Amino acid or sequencing procedure703/11, Biological or biochemical930/200, Bacterial peptide or bacterial protein (See note 6)930/240Enzyme or isoenzyme

Examiners

Primary: Lall, Parshotam S.
Assistant: Mattson, Brian M.

Attorney, Agent or Firm

Saidman, Sterne, Kessler & Goldstein

International Classes

C12N 9/52 (20060101)
C12N 9/54 (20060101)
G06F 19/00 (20060101)
C07K 1/00 (20060101)
C07K 1/113 (20060101)

Abstract

A computer-based method evaluates the structure of a protein to thereby identify sites in the protein molecule at which the natural amino acid residues can be replaced with cysteine residues in order to permit the formation of a potentially stabilizing disulfide bond.

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