Patent 4847092 Issued on July 11, 1989. Estimated Expiration Date: August 19, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
This invention provides orally administerable pharmaceutical formulations having a semi-solid matrix containing a hydrophilic substance capable of creating channels in a hydrophobic carrier matrix thereby providing a sustained rate of release of an active agent from the formulation.
Other References
Chemical Abstracts, vol. 89: 80177 "Effect of Hydrophilization of Hydrophobic on Release Rate for Capsule", Terk, C. F. et al. J. Phar. Science 1978 67 (7), 935-9
Chemical Abstracts, vol. 91, 1979: 27262c "in vitro and in vivo Availability of Hydrophilized Phentoine from Capsule", Terk, C. F. et al. J. Phar. Sci. 1979, 68 (5) 634-8
Product Bulletin, "The Hard Capsule with the Soft Centre", Elanco Products