Method for detecting tetrahydrocannabinol in human urine involving melanin precipitation
Patent 4843020 Issued on June 27, 1989. Estimated Expiration Date: 
January 14, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
January 14, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMethods and compounds for producing specific antibodies Method for detecting organic vapors Patent #: 4353886 InventorApplicationNo. 07/143973 filed on 01/14/1988US Classes:436/518, INVOLVING AN INSOLUBLE CARRIER FOR IMMOBILIZING IMMUNOCHEMICALS436/161, INCLUDING CHROMATOGRAPHY436/173, NUCLEAR MAGNETIC RESONANCE, ELECTRON SPIN RESONANCE OR OTHER SPIN EFFECTS OR MASS SPECTROMETRY436/175, Digestion or removing interfering materials436/177, Liberation or purification of sample or separation of material from a sample (e.g., filtering, centrifuging, etc.)436/536, INVOLVING IMMUNE COMPLEX FORMED IN LIQUID PHASE436/804, RADIOISOTOPE (E.G., RADIOIMMUNOASSAY, ETC.)436/816, Alkaloids, amphetamines, and barbiturates436/825, PRETREATMENT FOR REMOVAL OF INTERFERING FACTORS FROM SAMPLE436/901DRUGS OF ABUSE (E.G., NARCOTICS, AMPHETAMINE, ETC.)ExaminersPrimary: Marantz, SidneyAttorney, Agent or FirmInternational ClassG01N 33/94 (20060101)AbstractAn improved method for the detection of tetrahydrocannabinol in human urine wherein the pigment melanin is precipitated out of the urine prior to analysis with a solution of nitroferricyanide so that the melanin does not interfere with the analysis. The value attributable to melanin can also be subtracted from the value obtained during the analysis of the urine. The precipitation of melanin prior to analysis or subtraction of the melanin value during analysis greatly reduces the occurrence of false positive test results for persons with dark skin.Field of SearchDigestion or removing interfering materialsAlkaloids, amphetamines, and barbiturates PRETREATMENT FOR REMOVAL OF INTERFERING FACTORS FROM SAMPLE DRUGS OF ABUSE (E.G., NARCOTICS, AMPHETAMINE, ETC.) INCLUDING CHROMATOGRAPHY NUCLEAR MAGNETIC RESONANCE, ELECTRON SPIN RESONANCE OR OTHER SPIN EFFECTS OR MASS SPECTROMETRY Liberation or purification of sample or separation of material from a sample (e.g., filtering, centrifuging, etc.) INVOLVING IMMUNE COMPLEX FORMED IN LIQUID PHASE RADIOISOTOPE (E.G., RADIOIMMUNOASSAY, ETC.) |
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