Patent References 2888383 3202714 3223647 Antibacterial oral preparations Antimicrobial compositions employing certain substituted alanines and certain t-amine oxides Antimicrobial compositions employing certain betaines and certain amine oxides Oral hygiene Anti-plaque agents Antimicrobial compositions Toothpaste with zeolite polishing agent InventorAssigneeApplicationNo. 07/081580 filed on 07/31/1987US Classes:424/54, Ammonia, amine, or derivative thereof (e.g., urea, etc.)424/49, DENTIFRICES (INCLUDES MOUTH WASH)424/52, Fluorine or fluorine compound containing424/57, Phosphate compound containing514/901MouthwashExaminersPrimary: Brown, Johnnie R.Assistant: Moezie, F. T. Attorney, Agent or FirmInternational ClassesA61K 8/44 (20060101)A61K 8/30 (20060101) A61Q 11/00 (20060101) AbstractA process for enhancing oral hygiene by reducing oral microflora and for inhibiting the formation of dental plaque by applying, to the oral cavity, a composition containing(a) 0.1 to 40 parts, by weight, of a higher alkyl-N-betaine, having the structure ##STR1## wherein N is a higher alkyl group of from 10-18 carbon atoms, and (b) 0.1 to 40 parts, by weight, of a higher alkyl-N, N-dimethylamine, having the structure ##STR2## wherein R is a higher alkyl group of from 10 to 18 carbon atoms, and (c) acid in an amount sufficient to adjust the pH of the composition from 4.5 to 7.5 when measured in an aqueous solution of components (a) and (b) in a orally acceptable carrier.Other References
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