Collagen matrix beads for soft tissue repair

Patent 4837285 Issued on June 6, 1989. Estimated Expiration Date:

September 8, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Abstract Claims Description Full Text

Patent References

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Inventors

Assignee

MediMatrix

Application

No. 07/093826 filed on 09/08/1987

US Classes:

530/356, Collagen523/105, Nonmedicated composition specifically intended for contact with living animal tissue or process of preparing; other than apparel524/21, Animal derived protein or polypeptide other than casein, e.g., blood, egg albumin, etc.602/50Amino acid, polypeptide, or protein

Examiners

Primary: Kight, John
Assistant: Nutter, Nathan M.

Attorney, Agent or Firm

Ebert; Michael

International Classes

A61K 9/70 (20060101)
A61L 15/64 (20060101)
A61L 15/44 (20060101)
C08L 89/00 (20060101)
C08L 89/06 (20060101)
A61L 15/16 (20060101)
A61L 15/32 (20060101)
A61L 27/24 (20060101)
A61L 27/00 (20060101)
A61L 27/56 (20060101)
A61L 27/58 (20060101)

Abstract

Collagen-based compositions for augmenting soft tissue, wound dressings, implants, injectable formulations or other drug delivery systems, comprising resorbable collagen matrix beads, the beads having an average pore size of from 50 to 350 microns, and the collagen comprising from 1 to 30% by volume of the beads, the collagen matrix being sufficiently open to stimulate cellular ingrowth therethrough and yet sufficiently stiff and non-compressible to fill and protect a wound, and the formulation being sufficiently moisture and gas permeable to prevent liquid pooling on a wound and to permit sufficient oxygen diffusion for promoting wound healing.