Novel controlled release formulations of tetracycline compounds
October 6, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3901942 Process for encapsulation of medicaments Isolation and recovery of calcium chloride complex of 7-dimethylamino-6-dimethyl l-6-deoxytetracycline hydrochloride Inhibition of ADH-stimulated osmotic water flow and aldosterone-stimulated sodium transport Process for the preparatin of -6-deoxytetracyclines Process for the preparation of -6-deoxytetracyclines Process for preparation of microcapsules Patent #: 4622244 InventorsAssigneeApplicationNo. 07/104917 filed on 10/06/1987US Classes:424/456, Gelatin424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/489, Particulate form (e.g., powders, granules, beads, microcapsules, and pellets)424/490, Coated (e.g., microcapsules)424/494, Cellulose derivatives424/497, Containing solid synthetic polymers424/499, Contains proteins or derivative or polysaccharides or derivative424/500, Contains natural gums and resins424/501Contains solid synthetic resinExaminersPrimary: Page, Thurman K.Attorney, Agent or FirmInternational ClassesA61K 31/65 (20060101)A61K 9/16 (20060101) A61K 9/50 (20060101) AbstractPharmaceutical compositions comprising spherical granules including thereon or therein a 7- or 9-akylamino-6-deoxy-6-demethyltetracycline or an acid-addition salt thereof blended with at least one excipient are adapted to control the rate of drug release in the stomach and in the intenstine in order not to produce nausea or dizziness upon oral administration during antibacterial therapy.Field of SearchParticulate form (e.g., powders, granules, beads, microcapsules, and pellets)Coated (e.g., microcapsules) Containing proteins and derivatives Cellulose derivatives Ethyl cellulose Gelatin Sustained or differential release type Discrete particles in supporting matrix Containing solid synthetic polymers Contains proteins or derivative or polysaccharides or derivative EXTRACT, BODY FLUID, OR CELLULAR MATERIAL OF UNDETERMINED CONSTITUTION DERIVED FROM ANIMAL IS ACTIVE INGREDIENT Contains solid synthetic resin | |
