Patent References 3598122 3598123 3870593 3923939 Slow release copper toxicant compositions Device consisting of copolymer having acetoxy groups for delivering drugs Method and composition for the long term controlled release of a non-persistent organotin pesticide from an inert monolithic thermoplastic material Osmotic bursting drug delivery device Therapeutic system for administering drugs to the skin Dissolution controlled active agent dispenser InventorsAssigneeApplicationNo. 07/230211 filed on 08/09/1988US Classes:424/449, Transdermal or percutaneous424/486Synthetic polymerExaminersPrimary: Page, Thurman K.Assistant: Horne, L. Attorney, Agent or FirmInternational ClassA61K 9/70 (20060101)AbstractA diffusional drug delivery device is described which can provide for stability of the adhesive and system components, elimination of the initial burst of drug and hence irritation, and to provide for delayed onset of therapeutic effect along with delivery of a therapeutic agent at an optimum rate. The therapeutic agent in a first form which is suitable for storage, and the anhydrous activating means are inert when in an anhydrous environment. Moisture activates the system whereby the activating means provides an acidic or basic solution and the first form of the therapeutic agent is converted to a second form which is suitable for absorption through the skin or mucosa.Other References
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