Agonists and antagonists to nicotine as smoking deterents
Patent 4835162 Issued on May 30, 1989. Estimated Expiration Date: 
February 12, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
February 12, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.InventorApplicationNo. 07/014018 filed on 02/12/1987US Classes:514/305Quinuclidines (including unsaturation)ExaminersPrimary: Friedman, Stanley J.Attorney, Agent or FirmInternational ClassA61K 31/435 (20060101)AbstractAgonists and antagonists to nicotine are used as smoking deterrents.The nicotinic antagonists have the following structural requirements:(1) Aromatic, cycloalkyl, and heterocyclic carbamic acid esters of di- and trialkylaminoalkyl alcohols.(2) Aromatic, cycloalkyl, and heterocyclic thiocarbamic acid esters of di- and trialkylaminoalkyl alcohols.(3) Aromatic, cycloalkyl, and heterocyclic carboxylic acid esters of di- and trialkylaminoalkyl alcohols.(4) Aromatic, cycloalkyl, and heterocyclic carboxylic acid esters of heterocyclic amino alcohols.(5) Lobelia alkaloids: lobeline, lobelanine, and lobelanidine.The nicotinic agonists (nicotine-like) have the following structural requirements:(1) methylcarbamic acid esters of di- and trialkylaminoalkyl alcohols.(2) methylthiocarbamic acid esters of di- and trialkylaminoalkyl alcohols.Other References
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