Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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AbstractA solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water soluble cyclodextrin and a second substance selected from a C12 -C36 fatty alcohol and a polyalkylene glycol.Preferably the first substance is a cyclodextrin, especially a beta-cyclodextrin, while the second substance is a C14 -C22 fatty alcohol, especially stearyl alcohol, cetyl alcohol, cetostearyl alcohol or myristyl alcohol. The matrix may also contain a cellulose ether, especially a hydroxyalkylcellulose or a carboxyalkylcellulose. | InventorsAssigneeApplicationNo. 07/052585 filed on 05/19/1987US Classes:424/488, Polysaccharides (e.g., cellulose, etc.)424/457, Sustained or differential release424/458, Containing discrete coated particles pellets, granules, or beads424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/484, Matrices424/490, Coated (e.g., microcapsules)424/494, Cellulose derivatives424/499, Contains proteins or derivative or polysaccharides or derivative424/502, Contains waxes, higher fatty acids, higher fatty alcohols514/58, Dextrin or derivative514/965, Discrete particles in supporting matrix514/971, Crystallization point depressant or cold stabilizer containing536/103Dextrin or derivativeField of Search424/485, Natural gums, resin or latex424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof424/502, Contains waxes, higher fatty acids, higher fatty alcohols424/484, Matrices424/488, Polysaccharides (e.g., cellulose, etc.)424/457, Sustained or differential release424/458, Containing discrete coated particles pellets, granules, or beads424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/490, Coated (e.g., microcapsules)424/494, Cellulose derivatives424/499Contains proteins or derivative or polysaccharides or derivativeExaminersPrimary: Page, Thurman K.Attorney, Agent or FirmUS Patent References2921883, 3082154, 3084294, 3147187, 3492397, 3922339, 4722815Process of making a synthetic resin product containing a molecular inclusion compound in cyclodextrinIssued on: 02/02/1988 Inventor: Shibanai International ClassA61K 9/20 (20060101)Foreign Application Priority Data1986-06-05 GB |