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US Patent 4834985 - Controlled release pharmaceutical composition

US Patent Issued on May 30, 1989
Estimated Patent Expiration Date: Icon_subject May 19, 2007Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

A solid, controlled release, pharmaceutical composition comprising an active ingredient incorporated in a matrix comprising a first substance selected from a water soluble polydextrose and a water soluble cyclodextrin and a second substance selected from a C12 -C36 fatty alcohol and a polyalkylene glycol.Preferably the first substance is a cyclodextrin, especially a beta-cyclodextrin, while the second substance is a C14 -C22 fatty alcohol, especially stearyl alcohol, cetyl alcohol, cetostearyl alcohol or myristyl alcohol. The matrix may also contain a cellulose ether, especially a hydroxyalkylcellulose or a carboxyalkylcellulose.

Inventors

Assignee

Application

No. 07/052585 filed on 05/19/1987

US Classes:

424/488, Polysaccharides (e.g., cellulose, etc.)424/457, Sustained or differential release424/458, Containing discrete coated particles pellets, granules, or beads424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/484, Matrices424/490, Coated (e.g., microcapsules)424/494, Cellulose derivatives424/499, Contains proteins or derivative or polysaccharides or derivative424/502, Contains waxes, higher fatty acids, higher fatty alcohols514/58, Dextrin or derivative514/965, Discrete particles in supporting matrix514/971, Crystallization point depressant or cold stabilizer containing536/103Dextrin or derivative

Field of Search

424/485, Natural gums, resin or latex424/498, Containing waxes, higher fatty acids, higher fatty alcohols, or derivatives thereof424/502, Contains waxes, higher fatty acids, higher fatty alcohols424/484, Matrices424/488, Polysaccharides (e.g., cellulose, etc.)424/457, Sustained or differential release424/458, Containing discrete coated particles pellets, granules, or beads424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix424/490, Coated (e.g., microcapsules)424/494, Cellulose derivatives424/499Contains proteins or derivative or polysaccharides or derivative

Examiners

Primary: Page, Thurman K.

Attorney, Agent or Firm

US Patent References

2921883, 3082154, 3084294, 3147187, 3492397, 3922339, 4722815Process of making a synthetic resin product containing a molecular inclusion compound in cyclodextrin
Issued on: 02/02/1988
Inventor: Shibanai

International Class

A61K 9/20 (20060101)

Foreign Application Priority Data

1986-06-05 GB

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