Controlled release pharmaceutical composition
Patent 4834965 Issued on May 30, 1989. Estimated Expiration Date: 
November 12, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 12, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesProlonged release drug dosage forms based on modified low viscosity grade hydroxypropylmethylcellulose Patent #: 4540566 InventorsAssigneeApplicationNo. 07/119733 filed on 11/12/1987US Classes:424/488Polysaccharides (e.g., cellulose, etc.)ExaminersPrimary: Davis, Curtis R.Attorney, Agent or FirmInternational ClassA61K 9/20 (20060101)Foreign Application Priority Data1985-07-26 FRAbstractA solid, controlled release pharmaceutical composition is provided with enhanced levels of control over drug release. The composition comprises an acid addition salt or a quarternary ammonium salt of an organic base drug complexed with an anionic surfactant and distributed in a matrix of a hydrophilic polymer. The complex formation between the drug which is preferably an acid addition salt of an organic an organic amine, and the surfactant, which is preferably a sulphosuccinate, distributed in the hydrophilic polymer matrix, which is preferably a water soluble hydroxyalkylcelulose ether results in a composition with excellent controlled released characteristics. | |
