Patent ReferencesEffervescent tablet and method Effervescent enteric-coated formulation of soluble form of erythromycin and therapeutic use thereof Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion: expanded range Effervescent composition and method of making same Therapeutic effervescent composition Granular delayed-release form of pharmaceutically active substances Patent #: 4728513 InventorsApplicationNo. 07/056478 filed on 05/19/1987US Classes:424/466, Effervescent424/468, Sustained or differential release type424/479, Containing polysaccharide (e.g., sugar, etc.)424/480, Cellulose or derivative424/482Containing solid synthetic polymersExaminersPrimary: Lusignan, Michael R.Attorney, Agent or FirmInternational ClassesA61K 9/20 (20060101)A61K 9/46 (20060101) Foreign Application Priority Data1985-09-25 CHAbstractA desintegration tablet contains the filler material in a form and/or size which when coming in contact with water at ambient temperature dissolves so slowly that the water absorption and the action of the desintegration agent are not affected. The grains are either coated with a layer of slowly dissolving substance, in particular a colloid or pseudo-colloid, or consist of a crushed melted substance having a grain size preferably of between 0.2 and 0.6 mm, e.g. mannitol, sorbital and/or xylitol. | |