U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix

Patent 4832953 Issued on May 23, 1989. Estimated Expiration Date: Icon_subject August 13, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

Method and therapeutic system for administering scopolamine transdermally
Patent #: 4262003
Issued on: 04/14/1981
Inventor: Urquhart ,   et al.

Method for administering scopolamine transdermally
Patent #: 4436741
Issued on: 03/13/1984
Inventor: Urquhart ,   et al.

Method of treating migraine headaches
Patent #: 4532244
Issued on: 07/30/1985
Inventor: Innes

Medicaments with a high degree of solubility and method for their production Patent #: 4610875
Issued on: 09/09/1986
Inventor: Panoz ,   et al.

Inventors

Application

No. 07/085052 filed on 08/13/1987

US Classes:

424/448, Pressure sensitive adhesive means424/449Transdermal or percutaneous

Examiners

Primary: Page, Thurman K.

Attorney, Agent or Firm

International Class

A61K 9/70 (20060101)

Abstract

A method for preventing the formation of crystalline hydrates in a dispersion of a hydratable liquid in a nonaqueous matrix is disclosed. The method is particularly useful in the manufacture of laminated items formed from such dispersions and comprises forming individual subunits from such dispersions, heating the subunits, preferably after they have been packed in sealed containers, to a temperature high enough to melt the crystalline hydrate, maintaining said subunits at such temperature for a time sufficient to melt all the crystalline hydrate present and to prevent the occurrence of crystals for an extended period of time after cooling and cooling subunits to ambient conditions. The use of the method in the manufacture of transdermal delivery devices for the delivery of scopolamine base is described.

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