Method and therapeutic system for administering scopolamine transdermally
Method for administering scopolamine transdermally
Method of treating migraine headaches
Medicaments with a high degree of solubility and method for their production Patent #: 4610875
ApplicationNo. 07/085052 filed on 08/13/1987
US Classes:424/448, Pressure sensitive adhesive means424/449Transdermal or percutaneous
ExaminersPrimary: Page, Thurman K.
Attorney, Agent or Firm
International ClassA61K 9/70 (20060101)
AbstractA method for preventing the formation of crystalline hydrates in a dispersion of a hydratable liquid in a nonaqueous matrix is disclosed. The method is particularly useful in the manufacture of laminated items formed from such dispersions and comprises forming individual subunits from such dispersions, heating the subunits, preferably after they have been packed in sealed containers, to a temperature high enough to melt the crystalline hydrate, maintaining said subunits at such temperature for a time sufficient to melt all the crystalline hydrate present and to prevent the occurrence of crystals for an extended period of time after cooling and cooling subunits to ambient conditions. The use of the method in the manufacture of transdermal delivery devices for the delivery of scopolamine base is described.