Patent 4832686 Issued on May 23, 1989. Estimated Expiration Date: June 24, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
604/500, Method264/4.6, Solid-walled microcapsule formed by physically removing a constituent (e.g., evaporation, extraction, etc.)424/426, Errodable, resorbable, or dissolving424/463, Coated capsules424/486, Synthetic polymer424/487, Acrylic acid and derivatives424/85.2, Interleukin514/885, IMMUNE RESPONSE AFFECTING DRUG514/965, Discrete particles in supporting matrix604/891.1Implanted dynamic device or system
A biocompatible, biodegradable, bioerodible composite polymer matrix comprising interleukin-2 in an appropriate polymer. The polymer may be a polymer or copolymer of lactic acid, lactide, glycolide, glutamic acid, or it may be collagen or albumin. The material contains from 102 to 108 U IL-2/g of polymer. Also disclosed is a method for making the composite polyer matrix and a method for implanting the material. A soft, malleable controlled-release composite material may be used for intracranial or other implantation and may be shaped or molded to fit the site from which malignant tissue has been removed, opposing the residual tumor, complementing hemostasis, compatible with anatomical structure, and functioning as an implantable immunotherapeutic adjuvant.
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June 24, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
