Preparation of pharmaceutical grade amino acid chelates
Patent 4830716 Issued on May 16, 1989. Estimated Expiration Date: 
July 3, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
July 3, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesBuffered enzymatically produced metal proteinates Soluble non-ferrous metal proteinates Soluble iron proteinates Dipeptide sweetener-metal complexes Pure amino acid chelates Patent #: 4599152 InventorAssigneeApplicationNo. 06/882150 filed on 07/03/1986US Classes:205/457, Metal containing compound produced205/435, -COO- group containing205/799, MISCELLANEOUS ELECTROLYSIS556/116, Nitrogen containing556/134, Nitrogen containing (e.g., zinc ethionates, etc.)556/148, Nitrogen containing (e.g., ferric chelates of ethylenediaminetetracetic acid, etc.)556/50Nitrogen containingExaminersPrimary: Shaver, Paul F.Attorney, Agent or FirmInternational ClassesC07C 51/41 (20060101)C07C 51/41 (20060101) AbstractPharmaceutical grade amino acid chelates, free of interfering anions, are made by reacting an amino acid ligand with a metal member selected from the group consisting of elemental metals, metal oxides, metal hydroxides and metal carbonates in an aqueous environment wherein the ligand to metal mole ratio is at least 2:1 and recovering the amino acid chelate from said aqueous environment by means of spray or drum drying. The reaction may be carried out in the presence of non-interfering anions such as anions from citric acid, ascorbic acid, acetic acid, carbonic acid and ammonium and alkali metal salts thereof. |
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