Optimized capacitive sensor for chemical analysis and measurement
May 18, 2007. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesMethod for studying enzymatic and other biochemical reactions Electrochemiluminescent immunoassay and apparatus therefor Analytical device having semiconductive organic polymeric element associated with analyte-binding substance Lipid membrane electroanalytical elements and method of analysis therewith Diagnostic device incorporating a biochemical ligand Specific material detection and measuring device Patent #: 4571543 InventorAssigneeApplicationNo. 07/050367 filed on 05/18/1987US Classes:422/82.01, Measuring electrical property324/687, Having fringing field coupling422/69, Sorption testing422/90, With conductiometric detector422/98, Analysis based on electrical measurement435/817, ENZYME OR MICROBE ELECTRODE436/528, Carrier is organic436/806ELECTRICAL PROPERTY OR MAGNETIC PROPERTYExaminersPrimary: Marcus, Michael S.Attorney, Agent or FirmInternational ClassesG01N 27/22 (20060101)G01N 27/414 (20060101) G01N 27/403 (20060101) G01N 33/543 (20060101) AbstractAn apparatus for detecting the presence and/or measuring the concentration of an analyte in the fluid medium is disclosed. The apparatus relies on biospecific binding between a biochemical binding system and the analyte to change the dielectric properties of a capacitive affinity sensor. The biological affinity sensor is optimized by: (1) adjusting the thickness and dielectric properties of a passivation layer to generally match the impedance of the biological binding system; and (2) minimize the double layer capacitance so that bulk capacitance changes associated with the biological binding system are maximized. |
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