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US Patent 4820506 - Salivary stimulant

US Patent Issued on April 11, 1989
Estimated Patent Expiration Date: Icon_subject May 1, 2007Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
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Abstract

An aqueous liquid for promoting the production of human saliva in situ comprises:(a) about 2 to 3 wgt percent organic acidulent such as citric, malic, or ascorbic acid;(b) about 0.5 to 2.5 wgt percent of a natural, food-grade sweetener such as fructose or 0.05 to 0.5 wgt percent of a synthetic sweetener such as aspartame or saccharin; and(c) a saturated calcium phosphate solution.The preferred form of the aqueous liquid is a metered, hand-actuated, aerosol spray of about 0.15 ml. per actuation.By employing the aqueous liquid of the invention the production of saliva is tripled, thus alleviating the many symptoms of xerostomia no matter what its cause.

Inventors

Assignee

Application

No. 07/045618 filed on 05/01/1987

US Classes:

424/40, COMBUSTIBLE OR CHEMICALLY REACTIVE TO PRODUCE A SMOKE, MIST OR AEROSOL424/493, Containing polysaccharides (e.g., sugars)426/548, Noncarbohydrate sweetener or composition containing same426/650, Flavor or flavor adjunct, acidulant or condiment426/658Carbohydrate containing

Field of Search

426/3, NORMALLY NONINGESTIBLE CHEWABLE MATERIAL OR PROCESS OF PREPARATION426/72, PRODUCT WITH ADDED VITAMIN OR DERIVATIVE THEREOF FOR FORTIFICATION426/658, Carbohydrate containing426/548Noncarbohydrate sweetener or composition containing same

Examiners

Primary: Robinson, Ellis P.
Assistant: Ryan, J. P.

Attorney, Agent or Firm

US Patent References

4059686, Pharmaceutical preparation for oral cavity administration
Issued on: 11/22/1977
Inventor: Tanaka ,   et al.
4088788, Saliva stimulating chewing gum composition
Issued on: 05/09/1978
Inventor: Ream, et al.
4452820, Gum base and chewing gum containing same
Issued on: 06/05/1984
Inventor: D'Amelia ,   et al.
4472437, Dicalcium phosphate as gum base filler
Issued on: 09/18/1984
Inventor: Corsello ,   et al.
4515770, Food materials for prevention of carious degradation of teeth
Issued on: 05/07/1985
Inventor: Besic
4537689, Oral lubricant for athletic mouth protector
Issued on: 08/27/1985
Inventor: Morrow ,   et al.
4715369, Method of treating an injured part on the oral mucosa and the covering material for use thereof
Issued on: 12/29/1987
Inventor: Suzuki ,   et al.
4726953Sweet flavorful soft flexible sugarless chewing gum
Issued on: 02/23/1988
Inventor: Carroll ,   et al.

International Class

A61K 33/42 (20060101)

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