Transdermal multipolymer drug delivery system
Patent 4814168 Issued on March 21, 1989. Estimated Expiration Date: 
March 4, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
March 4, 2008. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent ReferencesDevice consisting of copolymer having acetoxy groups for delivering drugs Pressure-sensitive adhesive tape or pressure-sensitive adhesive sheet containing nitroglycerin Transdermal drug patches Dermal and transdermal patches having a discontinuous pattern adhesive layer Patent #: 4743249 InventorsAssigneeApplicationNo. 07/164482 filed on 03/04/1988US Classes:514/182, Oxygen single bonded to a ring carbon of the cyclopentanohydrophenanthrene ring system424/448, Pressure sensitive adhesive means424/449, Transdermal or percutaneous424/484, Matrices424/485, Natural gums, resin or latex424/486, Synthetic polymer514/504, Arsenic514/772.4Polymer from ethylenic monomers onlyExaminersPrimary: Page, Thurman K.Assistant: Horne, Leon R. Attorney, Agent or FirmInternational ClassesA61F 13/02 (20060101)A61K 9/70 (20060101) A61L 15/58 (20060101) A61L 15/18 (20060101) A61L 15/16 (20060101) AbstractA dermal compositon comprising a drug, a multi-polymer of vinyl acetate, polyethylene and optionally one or more monomers, a natural or synthetic rubber and a tackifying agent. The ratio of the multipolymer to the rubber is, respectively, about 1:1 to about 10:1 and more preferably 1:1 to 5:1 and more preferably 3:1. The dermal composition can optionally contain a crosslinking agent, tackifiers, penetration enhancers and other ingredients known for use in adhesives for the transdermal delivery of drugs. The dermal compositions can be produced by a variety of methods known in the preparation of drug containing adhesive preparations including the homogenous mixing of the multi-polymer, drug and optional crosslinking agent and additional ingredients in aqueous solution followed by removal of excess water.Other References
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