Erodible matrix for sustained release bioactive composition
Patent 4806337 Issued on February 21, 1989. Estimated Expiration Date: 
October 14, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
October 14, 2006. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3336155 3634584 3641236 Growth promotant controlled release formulations and method of treatment Drug delivery devices comprising erodible polymer and erosion rate modifier Process for the preparation of tablets with retarded liberation of the active agent is predetermined Erodible matrix for sustained release bioactive composition Patent #: 4629621 InventorsAssigneeApplicationNo. 06/918273 filed on 10/14/1986US Classes:504/360, Solid resin containing (e.g., film-forming resins, etc.)424/408, Capsule or pelleted or tablet424/457, Sustained or differential release424/465, With claimed perfecting feature in contents (e.g., excipient, lubricant, etc.)424/468, Sustained or differential release type424/469, Discrete particles in supporting matrix428/402.24, Microcapsule with solid core (includes liposome)514/772, DESIGNATED ORGANIC NONACTIVE INGREDIENT CONTAINING OTHER THAN HYDROCARBON514/784, Carboxylic acid or salt thereof71/64.11Controlled releaseExaminersPrimary: Kight, JohnAssistant: Moore, M. L. Attorney, Agent or FirmInternational ClassA61K 9/20 (20060101)AbstractA sustained release composition for releasing a biologically active compound into an aqueous liquid environment comprises said biologically active compound dispersed in a bioerodible matrix, the matrix comprising a mixture of (a.) 5% to 95% by weight of a solid water-dispersible polyether diol having a molecular weight from about 1000 to about 20,000K selected from the group consisting of polyethylene glycols and polyethylene oxide-polypropylene oxide block copolymers, and(b.) 95 to 5% by weight of an erosion rate modifier which is an amphiphilic compound insoluble in the aqueous liquid.Dosage forms comprising the erodible matrix are prepared by molding, particularly by injection molding. | |
